Author

Denis Houzelstein

Centre National de la Recherche ScientifiqueORCID 0000-0002-8536-9039Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Ana CumanoiD· 1 shared Anu BashambooiD· 1 shared Asma BoukriiD· 1 shared Dominique Simon‐Chazottes· 1 shared Grégory JouvioniD· 1 shared Housna Zidoune· 1 shared Jean‐Jacques PanthieriD· 1 shared Joëlle Bignon‐Topalovic· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Ana CumanoORCID

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2 papers

Recent·Most cited

Evidence for NR2F2/COUP-TFII involvement in human testis development

Somboon Wankanit, Housna Zidoune, Joëlle Bignon‐Topalovic, Laurène Schlick, Denis Houzelstein, Leïla T. S. Fusée, Asma Boukri, Nassim Nouri, Ken McElreavey, Anu Bashamboo, Maëva Elzaïat

The paper investigates the role of NR2F2/COUP-TFII in human testis development by analyzing a pathogenic variant in a 46,XY DSD patient and shows its impact on steroidogenic lineage activation.

bioRxiv · Jan 5, 2024 · PreprintMolecular Biology

Genetic dissection of Rift Valley fever pathogenesis: Rfvs2 on mouse chromosome 11 enables survival to acute-onset hepatitis

Leandro Batista, Grégory Jouvion, Dominique Simon‐Chazottes, Denis Houzelstein, Odile Burlen‐Defranoux, Magali Boissière, Satoko Tokuda, Tânia Zaverucha do Valle, Ana Cumano, Marie Flamand, Xavier Montagutelli, Jean‐Jacques Panthier

This study identifies Rvfs2 as a genetic locus that restricts RVFV replication and enables survival from acute liver disease in mice.

bioRxiv · Feb 8, 2019 · PreprintGenetics