Author

Somboon Wankanit

Centre National de la Recherche ScientifiqueORCID 0000-0002-7171-6597Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Anu BashambooiD· 3 shared Ken McElreaveyiD· 3 shared Maëva ElzaïatiD· 3 shared Caroline EozénouiD· 2 shared Joëlle Bignon‐Topalovic· 2 shared Laurène SchlickiD· 2 shared Pierre‐Henri CommèreiD· 2 shared Almira A. ChervovaiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCell Biology

Anu BashambooORCID

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3 papers

Recent·Most cited

Altered RNA-processing provides a mechanistic framework delineating human sex reversal associated with pathogenic variants in the RNA-helicase DHX37

Maëva Elzaïat, Estelle Talouarn, Somboon Wankanit, Laurène Schlick, Caroline Eozénou, Joëlle Bignon‐Topalovic, Étienne Kornobis, Pierre‐Henri Commère, Chloé Baum, Valérie Seffer, Ken McElreavey, Anu Bashamboo

This study identifies how DHX37 variants disrupt RNA processing and gene expression in Sertoli-like cells, leading to 46,XY sex reversal.

bioRxiv · Jan 10, 2025 · PreprintCell Biology

Evidence for NR2F2/COUP-TFII involvement in human testis development

Somboon Wankanit, Housna Zidoune, Joëlle Bignon‐Topalovic, Laurène Schlick, Denis Houzelstein, Leïla T. S. Fusée, Asma Boukri, Nassim Nouri, Ken McElreavey, Anu Bashamboo, Maëva Elzaïat

The paper investigates the role of NR2F2/COUP-TFII in human testis development by analyzing a pathogenic variant in a 46,XY DSD patient and shows its impact on steroidogenic lineage activation.

bioRxiv · Jan 5, 2024 · PreprintMolecular Biology

In-vitro cellular reprogramming to model gonad development and its disorders

Nitzan Gonen, Caroline Eozénou, Richard Mitter, Maëva Elzaïat, Isabelle Stévant, Rona Aviram, Andreia Sofia Bernardo, Almira A. Chervova, Somboon Wankanit, Emmanuel Frachon, Pierre‐Henri Commère, Sylvie Brailly‐Tabard, Léo Valon, Laura Barrio Cano, Romain Levayer, , Anu Bashamboo

This paper describes in-vitro protocols to differentiate mouse and human pluripotent cells into gonadal progenitors, revealing their functional equivalence to in-vivo cells and modeling DSDs.

Science Advances · Jan 4, 2023Peer-reviewedDevelopmental Biology