Sanwen Huang

The paper constructs an agent-ready potato multi-omics database and develops Potato Agent to enable natural-language-driven bioinformatics analysis and functional gene discovery in potato.

The paper constructs a cucumber pangenome to analyze structural variant dynamics during domestication and breeding, finding SVs are purged more than SNPs and improving genomic prediction accuracy.

This study examines hemizygous genes in 22 crop genomes, finding higher hemizygosity in clonal lineages and distinct expression and epigenetic features compared to diploid genes.

This paper demonstrates that ONT Duplex sequencing combined with Pore-C data can assemble complete, high-quality human and plant chromosomes with base accuracy over 99.999%.

This paper introduces PGGB, a pipeline for building pangenome graphs that includes all variation without bias, enabling variation detection, conservation measurement, recombination event detection, and phylogenetic inference.

The paper presents a high-quality reference genome for tomato, revealing genomic fragments linked to human selection during domestication.

The paper presents a chromosome-level genome of Taxus chinensis var. mairei, revealing unique genome evolution and genetic structures for paclitaxel biosynthesis.

This study identifies genomic bases of peach local adaptation to climate variables using re-sequencing and environmental association analyses.

This study shows that asexual lineages of the potato blight pathogen Phytophthora infestans are mostly triploid, linking ploidy level to reproductive mode and virulence.