Author
Zhigui Bao
Max Planck Institute for BiologyORCID 0000-0003-3601-460XUnclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2024-2026 · peak 6/yrCo-Author Collaboration Network
10 top collaborators · 27 mutual co-author links9 papers
Recent·Most cited
- Evolutionary BiologybioRxivPreprint
Overcoming breeding constraints in polyploid oat from evolutionary insights
Xue Bai, Miao Sun, Yue Zhang…·Yao Zhou
This study uses genome and transcriptomic analyses of oat species to show that polyploidy creates functional redundancy, buffering mutations but hindering beneficial allele fixation, and proposes breeding strategies to overcome these challenges.
- Evolutionary BiologybioRxivPreprint
The structure of mitochondrial genomes is associated with geography in Arabidopsis thaliana
Wenfei Xian, Zhigui Bao, Sebastian Vorbrugg…·Detlef Weigel
This study analyzes mitochondrial and chloroplast genomes of Arabidopsis thaliana to show that large repeats correlate with geography and phenotypes, and identify novel ORFs potentially from horizontal gene transfer.
- GenomicsbioRxivPreprint
The 1001G+ project: A curated collection of Arabidopsis thaliana long-read genome assemblies to advance plant research
Carlos Alonso‐Blanco, Haim Ashkenazy, Pierre Baduel…·Wenfei Xian
The paper curates and presents a collection of long-read genome assemblies for Arabidopsis thaliana accessions to enhance plant genome research.
- BioinformaticsbioRxivPreprint
Gfa2bin enables graph-based GWAS by converting genome graphs to pan-genomic genotypes
Sebastian Vorbrugg, Ilja Bezrukov, Zhigui Bao…·Detlef Weigel
Gfa2bin converts genome graphs to pan-genomic genotypes for GWAS, identifying additional associations with higher significance than SNP-based approaches in Arabidopsis thaliana.
- BioinformaticsGenome ResearchPeer-reviewed
Gapless assembly of complete human and plant chromosomes using only nanopore sequencing
Sergey Koren, Zhigui Bao, Andrea Guarracino…·Adam M. Phillippy
This paper demonstrates that ONT Duplex sequencing combined with Pore-C data can assemble complete, high-quality human and plant chromosomes with base accuracy over 99.999%.
52 citations - BioinformaticsNature MethodsPeer-reviewed
Building pangenome graphs
Erik P. Garrison, Andrea Guarracino, Simon Heumos…·Pjotr Prins
This paper introduces PGGB, a pipeline for building pangenome graphs that includes all variation without bias, enabling variation detection, conservation measurement, recombination event detection, and phylogenetic inference.
279 citationstop 1% - GenomicsbioRxivPreprint
TIPPo: A User-Friendly Tool for De Novo Assembly of Organellar Genomes with HiFi Data
Wenfei Xian, Ilja Bezrukov, Zhigui Bao…·Detlef Weigel
TIPPo assembles organellar genomes using HiFi data without reference genomes or nuclear information, achieving complete chloroplast assemblies and improved mitochondrial results compared to existing tools.