NeuroscienceDisease Models & MechanismsPeer-reviewed
Systemic HIV-1 Infection Produces a Unique Glial Footprint in Humanized Mouse Brains
Weizhe Li, Santhi Gorantla, Howard Eliot Gendelman, Larisa Y. Poluektova
This paper creates a humanized mouse model to study HIV-1's effects on glial cells, finding human-specific transcriptional changes in antiviral responses and myelination.
26 citations