Molecular BiologybioRxivPreprint
Integrating pharmacogenomics data-driven prediction with bulk and single-cell RNAseq to demonstrate the efficacy of an NAMPT inhibitor against aggressive, taxane-resistant, and stem-like cells in lethal prostate cancer
Suman Mazumder, Taraswi Mitra Ghosh, Ujjal Kumar Mukherjee…·Amit Mitra
The paper uses scRNAseq and pharmacogenomics to identify FK866 as a potential drug for aggressive prostate cancer, showing its efficacy against drug-resistant and stem-like cells.
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