Author

Isra A. Elhussin

Tuskegee UniversityORCID 0000-0002-4141-8783Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:matrix factorization· 1 Assay:scRNA-seq· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Clayton Clopton YatesiD· 2 shared Ademola Alabi PopoolaiD· 1 shared Ahmad-Bin Salam· 1 shared Amit MitraiD· 1 shared Balasubramanyam KaranamiD· 1 shared Chidiebere Ndukwe Ogo· 1 shared Damali N. MartiniD· 1 shared Damian K Francis· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Clayton Clopton YatesORCID

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Author profile →

2 papers

Recent·Most cited

Whole Exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry

Jason A. White, Ernest T. Kaninjing, Kayode Adebamiji Adeniji, Paul Jibrin, John Oladapo Obafunwa, Chidiebere Ndukwe Ogo, Mohammed Faruk, Ademola Alabi Popoola, Omolara Aminat A. Fatiregun, Olabode Peter Oluwole, Balasubramanyam Karanam, Isra A. Elhussin, Stefan Ambs, Wei Tang, Melissa Boneta Davis, , Clayton Clopton Yates

This study analyzes whole-exome sequencing data from Nigerian prostate cancer tumors to identify germline and somatic variants associated with African ancestry and DNA repair gene mutations.

Cancer Research Communications · Sep 16, 2022Peer-reviewedGenetic & Genomic Medicine

Integrating pharmacogenomics data-driven prediction with bulk and single-cell RNAseq to demonstrate the efficacy of an NAMPT inhibitor against aggressive, taxane-resistant, and stem-like cells in lethal prostate cancer

Suman Mazumder, Taraswi Mitra Ghosh, Ujjal Kumar Mukherjee, Sayak Chakravarti, Farshad Amiri, Farnaz Hemmati, Panagiotis Mistriotis, Isra A. Elhussin, Ahmad-Bin Salam, Windy Marie Dean-Colomb, Feng Li, Clayton Clopton Yates, Robert D. Arnold, Amit Mitra

The paper uses scRNAseq and pharmacogenomics to identify FK866 as a potential drug for aggressive prostate cancer, showing its efficacy against drug-resistant and stem-like cells.

bioRxiv · Jul 20, 2022 · PreprintMolecular Biology