Manuela Roggiani

Resident and Engrafting E. coli Populations Expand Through Dissimilar Pathways in the Inflamed Gut

This study shows that Moco is important for E. coli colonization in a healthy gut but not for inflammation-induced blooms, highlighting the role of colonization timing in microbial fitness.

Carbohydrate consumption drives adaptive mutations in Escherichia coli associated with increased risk for systemic infection

This study shows lactulose consumption selects for E. coli mutations that enhance its metabolic fitness and colonization, increasing infection risk in cirrhosis patients.