Mark Goulian

This study shows that Moco is important for E. coli colonization in a healthy gut but not for inflammation-induced blooms, highlighting the role of colonization timing in microbial fitness.

This study identifies platelet factor 4 (PF4) as a mediator of endothelial antimicrobial activity, enhancing bacterial clearance and improving sepsis outcomes through clathrin-mediated endocytosis and reduced immunothrombosis.

This study shows lactulose consumption selects for E. coli mutations that enhance its metabolic fitness and colonization, increasing infection risk in cirrhosis patients.