Author

Wangxin Guo

Chinese Academy of SciencesORCID 0000-0002-8578-6035Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

Dong GaoiD· 2 shared Hongjiong Zhang· 2 shared Anuradha GopalaniD· 1 shared Anurag SharmaiD· 1 shared Bin ZhouiD· 1 shared Chao LiangiD· 1 shared Chen Khuan WongiD· 1 shared Chen Yu· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

Dong GaoORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintFeb 16, 2026

Cell-Autonomous AR Dependence in Luminal Prostatic Epithelium Governs Survival and Lineage Plasticity

Dan Li, Naitao Wang, Wangxin Guo…·Yu Chen

This study shows that luminal prostatic epithelial cells depend on AR signaling for survival and differentiation, and their loss triggers compensatory pathways and lineage plasticity.

DOI 10.64898/2026.02.13.705807

mousebulk RNA-seq

𝕏 PostBluesky

Developmental BiologybioRxivPreprintMay 12, 2023

Intermediate basal cell population in prostate homeostasis and cancer initiation

Wangxin Guo, Xiaoyu Zhang, Lin Li…·Dong Gao

The paper identifies an intermediate basal cell population (Basal-B) in the prostate that shows lineage plasticity and contributes to both homeostasis and cancer initiation.

3 citations

mousescRNA-seq

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