Perturbation biology links temporal protein changes to drug responses in a melanoma cell line
Elin Nyman, Richard R. Stein, Xiaohong Jing, Weiqing Wang, Benjamin R. Marks, Ioannis K. Zervantonakis, Anil Korkut, Nicholas Paul Gauthier, Chris Sander
The paper develops a temporal modeling framework to link protein changes to drug responses in melanoma cells, identifying effective therapies through experimental validation.
PLoS Computational Biology · Jul 15, 2020Peer-reviewedSystems Biology