Richard R. Stein

This paper demonstrates how to directly measure intrinsic cooperativity from single binding assays using ternary complex formation between FKBP12, MAPRE1, and macrocyclic molecular glues.

The paper develops a temporal modeling framework to link protein changes to drug responses in melanoma cells, identifying effective therapies through experimental validation.

The paper evaluates the Zeptosens RPPA platform for protein profiling in cancer samples, demonstrating its sensitivity, reproducibility, and accuracy.