Djoher Nora Abrous

This study shows that adolescent sugar overconsumption disrupts hippocampal neuron function, leading to adult motivational issues in rats.

The paper identifies molecular and functional differences between suprapyramidal and infrapyramidal blades in the mouse dentate gyrus using multi-omics approaches.

The paper investigates how long-lived adult-born hippocampal neurons contribute to cognitive resilience in aging rats, showing their role in maintaining synaptic inputs and mitochondrial homeostasis.

The paper shows adult-born dentate granule neurons contribute to pattern completion, a process critical for episodic memory, with implications for mental health disorders.

This study evaluates the PenkCre mouse line as a tool to label and study embryonically-born dentate granule neurons in young mice.

This study shows that Vangl2 regulates adult hippocampal neurogenesis and cognitive flexibility in mice, with reduced Vangl2 leading to impaired memory and increased interference-based forgetting.

This study shows that prenatal stress impairs pattern separation in adult mice, potentially contributing to cognitive deficits and behaviors similar to psychiatric disorders.

This study shows that deleting S6K1 in adult mice causes anxiety-like behaviors and learning deficits, linked to reduced hippocampal neurogenesis and neuronal atrophy.

The paper shows that resilience to cognitive aging in rats is linked to the responsiveness of adult-generated neurons, not just their number.

This study compares the role of adolescent- and adult-born dentate granule neurons in spatial learning and finds that their ontogenetic stage determines their involvement in memory processes.