Author

Alberto Cassetta

National Research CouncilORCID 0000-0002-8600-4162Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alessandra MagistratoiD· 1 shared Alexandre DurandiD· 1 shared Ario de MarcoiD· 1 shared Bhavani GangupamiD· 1 shared Claudia D’ErcoleiD· 1 shared Cristian ParraiD· 1 shared Davide CotugnoiD· 1 shared Dihia MoussaouiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Alessandra MagistratoORCID

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1 paper

Recent·Most cited

Structural flexibility of the human vault protein revealed by high-resolution cryo-EM and molecular dynamics simulations

Fabio Lapenta, Karen Palacio‐Rodríguez, Sergio Cruz-León, Simone Marrancone, Jana Aupič, N. Marechal, Alexandre Durand, Dihia Moussaoui, Sonia Covaceuszach, Bhavani Gangupam, Claudia D’Ercole, Cristian Parra, Davide Cotugno, Giulia Tomaino, Paolo Tortora, , Gerhard Hummer

This study uses cryo-EM and molecular dynamics simulations to reveal structural flexibility in the human vault protein, identifying conformational states and dynamic assembly mechanisms.

bioRxiv · Aug 26, 2025 · PreprintBiochemistry