Author

N. Marechal

Institut de génétique et de biologie moléculaire et cellulaireORCID 0000-0002-4239-9625Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

N. Marechal1 paper

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1 Assay:cryo-EM· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Alexandre DurandiD· 2 shared Alberto CassettaiD· 1 shared Alessandra MagistratoiD· 1 shared Anna M. SteyeriD· 1 shared Ario de MarcoiD· 1 shared Bhavani GangupamiD· 1 shared Claudia D’ErcoleiD· 1 shared Corrine Crucifix· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

Alexandre DurandORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural flexibility of the human vault protein revealed by high-resolution cryo-EM and molecular dynamics simulations

Fabio Lapenta, Karen Palacio‐Rodríguez, Sergio Cruz-León, Simone Marrancone, Jana Aupič, N. Marechal, Alexandre Durand, Dihia Moussaoui, Sonia Covaceuszach, Bhavani Gangupam, Claudia D’Ercole, Cristian Parra, Davide Cotugno, Giulia Tomaino, Paolo Tortora, , Gerhard Hummer

This study uses cryo-EM and molecular dynamics simulations to reveal structural flexibility in the human vault protein, identifying conformational states and dynamic assembly mechanisms.

bioRxiv · Aug 26, 2025 · PreprintBiochemistry

Organisation of axial regions of isolated mitotic chromosomes visualised by cryo correlative light and electron tomography

Gurudatt Patra, Mohamad Harastani, Kumiko Samejima, Lucy Remnant, N. Troffer-Charlier, Corrine Crucifix, Alexandre Durand, N. Marechal, Yves Lutz, Anna M. Steyer, Zhengyi Yang, Wim J. H. Hagen, William C. Earnshaw, Mikhail Eltsov

The paper uses cryo-CLEM to visualize and analyze the ultrastructural organization of mitotic chromosomes, identifying non-histone macromolecular densities and surface particle clusters.

bioRxiv · Feb 6, 2025 · PreprintCell Biology

Single-stranded DNA drives sigma subunit loading onto RNA polymerase to unlock initiation-competent conformations

Rishi Kishore Vishwakarma, N. Marechal, Zakia Morichaud, Mickaël Blaise, Emmanuel Margeat, Konstantin L. Brodolin

The paper investigates how single-stranded DNA facilitates sigma subunit loading onto RNA polymerase, enabling the formation of the open promoter complex in Mycobacterium tuberculosis.

bioRxiv · Aug 21, 2024 · PreprintMolecular Biology