Regulation and function of trans-physeal growth plate bridges: evidence for a mechanical base isolation role to minimise epiphyseal shear stress
Dionysia Valkani, LAE Evans, Catherine Mary Disney, Aikta Sharma, B Javaheri, J Chen, RT Hansen, Mark Hopkinson, Samuel Monzem, Polymnia Louka, Andrew J. Bodey, Brian K. Bay, Peter David Lee, Katherine Ann Staines, Andrew A. Pitsillides
This study investigates the regulation and function of trans-physeal growth plate bridges in mice, finding they serve a mechanical role to reduce epiphyseal shear stress during bone growth.
bioRxiv · Feb 8, 2026 · PreprintBioengineering