Author

Kakularam Kumar Reddy

University of HyderabadORCID 0000-0002-8601-474XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Aradhana Mariam PhilipsiD· 1 shared Farhan AhmediD· 1 shared Harshavardhan Bhuktar· 1 shared Mahesh KumariD· 1 shared Manaswani Jagadeb· 1 shared Manojit PaliD· 1 shared Naireen Fatima· 1 shared Neha SharmaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Aradhana Mariam PhilipsORCID

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1 paper

Recent·Most cited

ALOX12B overexpression in the skin drives inflammasome/Th17 signaling axis to promote inflammation in the mouse model and human patients

Suman Singh, Farhan Ahmed, Naireen Fatima, Nikhith Cholleti Sai, Harshavardhan Bhuktar, Rafiq Ahmad Khan, Sumbul Afroz, Srikanth Battu, Kakularam Kumar Reddy, Manaswani Jagadeb, Saima Naz, Neha Sharma, Aradhana Mariam Philips, Tina Priscilla, Vaibhav Vindal, , Nooruddin Khan

This study identifies ALOX12B as a driver of skin inflammation through the inflammasome/Th17 signaling axis, showing its overexpression in psoriasis and atopic dermatitis and demonstrating a novel inhibitor's efficacy in a mouse model.

bioRxiv · Jun 9, 2025 · PreprintImmunology