Author

Mary R. Starich

National Institutes of HealthORCID 0000-0002-8603-4628Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Research Focus:protein structure prediction· 2 Approach:deep learning· 1 Approach:statistical model· 1

Frequent Co-Authors

Lauren L. PorteriD· 2 shared Marie‐Paule StrubiD· 2 shared Allen K. Kim· 1 shared Ananya K. MajumdariD· 1 shared Brett D. MenshiD· 1 shared Brian F. VolkmaniD· 1 shared Carolyn M. OttiD· 1 shared Davin R. JenseniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBioinformatics

Lauren L. PorterORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJul 21, 2026

AlphaFold reveals but sometimes distorts an organizational principle of protein folding

Madeleine F Clore, Joseph F. Thole, Suchetan Dontha…·Lauren L. Porter

The paper uses AlphaFold to identify gating residues that control conformational accessibility in proteins, finding that AlphaFold sometimes misapplies this principle.

2 citations

protein structuredeep learning

𝕏 PostBluesky

BioinformaticsNature CommunicationsPeer-reviewedJul 1, 2022

Many dissimilar protein domains switch between α-helix and β-sheet folds

Lauren L. Porter, Allen K. Kim, Swechha Rimal…·Marie‐Paule Strub

The paper identifies fold-switching proteins by analyzing secondary structure propensities in the NusG family, finding 25% of sequences undergo α-helix ↔ β-sheet transitions.

40 citations

protein structurestatistical model

𝕏 PostBluesky