Author

Swechha Rimal

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Adi LavyiD· 1 shared Allen K. Kim· 1 shared Ananya K. MajumdariD· 1 shared Antje KrügeriD· 1 shared Ashty S. KarimiD· 1 shared Brett D. MenshiD· 1 shared Divyesh A. Patel· 1 shared Erik KvamiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSynthetic Biology

Adi LavyORCID

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2 papers

Recent·Most cited

Scalable cell-free production of active T7 RNA polymerase

Ryan N. Rezvani, Rochelle Aw, Wei Chan, Krishnathreya Satish, Han Chen, Adi Lavy, Swechha Rimal, Divyesh A. Patel, Govind Rao, James R. Swartz, Matthew P. DeLisa, Erik Kvam, Ashty S. Karim, Antje Krüger, Weston Kightlinger, Michael C. Jewett

This paper demonstrates scalable cell-free production of active T7 RNA polymerase with high purity and activity, suitable for decentralized biotherapeutic manufacturing.

Biotechnology and Bioengineering · Apr 29, 2025Peer-reviewedSynthetic Biology

Many dissimilar protein domains switch between α-helix and β-sheet folds

Lauren L. Porter, Allen K. Kim, Swechha Rimal, Loren L. Looger, Ananya K. Majumdar, Brett D. Mensh, Mary R. Starich, Marie‐Paule Strub

The paper identifies fold-switching proteins by analyzing secondary structure propensities in the NusG family, finding 25% of sequences undergo α-helix ↔ β-sheet transitions.

Nature Communications · Jul 1, 2022Peer-reviewedBioinformatics