Ananya K. Majumdar

This study investigates how aromatic residues in E. coli DXPS stabilize the closed conformation of the enzyme during catalysis by analyzing mutagenesis effects on conformational dynamics.

This study investigates how trihydroxybenzaldoximes inhibit ThDP-dependent DXP synthase by acting as redox cycling agents, showing their oxidation under aerobic conditions enhances inhibitory activity.

This paper investigates how dynamic structural networks in IL-2 superkines affect receptor binding and signaling, showing that modulating core dynamics can improve immune cell selectivity.

The paper identifies fold-switching proteins by analyzing secondary structure propensities in the NusG family, finding 25% of sequences undergo α-helix ↔ β-sheet transitions.