Steven Woodhouse

The paper identifies immune exposure signatures by clustering T-cell receptors co-occurring across donors, linking them to specific pathogens and HLA alleles.

The paper provides a catalog of public T-cell receptors specific to cytomegalovirus (CMV) and explores their antigen specificity and subgroup variations.

Seq2MAIT identifies MAIT cells from bulk TCR-sequencing data using a transformer-based model, achieving AUROC >0.80 across datasets.

The paper uses single-cell RNA-seq and enhancer editing to study thalamic nuclei formation in mice, revealing lineage-specific gene expression programs and their role in neurodevelopmental disorders.

The paper introduces STvEA, a method that integrates single-cell RNA-seq with mIHC data to improve cell population annotation in cytometry datasets.