Shunhua Han

This study benchmarks CNV callers for WGS clinical applications, finding DRAGEN v4.2 offers the best balance of sensitivity and precision for detecting deletions and some duplications.

The paper introduces an improved pipeline for evaluating transposable element detectors in yeast, revealing best-in-class methods and novel biological insights.

The paper develops a method to analyze transposable elements in polyploid genomes using long-read sequencing, revealing somatic transposition events and TE family proliferation.

The paper sequenced 25 Drosophila S2 cell sub-lines to show ongoing transposition and use TE insertions for phylogenetic reconstruction in cell culture.

This paper develops a TE-based authentication protocol for Drosophila cell lines to improve reproducibility by distinguishing between different cell lines and sub-lines.

This paper uses transposable element profiles to identify and authenticate Drosophila cell lines and reveal loss of heterozygosity.

The paper analyzes P element insertions in Drosophila melanogaster populations to understand variation in gonadal dysgenesis phenotypes and shows that insertion numbers do not strongly correlate with phenotype severity.