Douglas B. Rusch

The paper identifies ERR-specific genomic targets in adult Drosophila adipocytes using NanoDam, revealing its role in regulating metabolic pathways.

This paper identifies and functionally characterizes vitamin K-based redox modules in giant viruses that modify host membrane lipids during infection.

This study identifies how CAP and LuxR co-regulate gene expression in Vibrio campbellii through synergistic or antagonistic promoter occupancy, revealing indirect regulation of bioluminescence.

This study identifies four T3SS-secreted effectors in V. campbellii that exhibit cytotoxicity in eukaryotic cells, highlighting conserved T3SS structure but variable effector repertoires across the Harveyi clade.

The paper examines sex differences in gene expression in northern jacanas to understand how sex roles influence neurogenomic profiles, finding complex genetic and hormonal interactions rather than simple reversal of sex-biased gene expression.

The paper investigates convergent evolution in cavity-nesting birds, finding behavioral similarities but limited gene expression convergence across species.

This study identifies a dual regulatory mechanism by LuxR in Vibrio campbellii that represses T3SS gene expression through transcriptional and post-translational repression of ExsA activity.

This study identifies an active quorum sensing pathway in Vibrio coralliilyticus that regulates virulence factors like proteases, biofilms, and type VI secretion systems.

This study identifies two temperature-regulated T6SSs in Vibrio coralliilyticus, revealing their roles in bacterial competition and host toxicity, with T6SS2 secreting nine novel anti-eukaryotic toxins.

The paper evaluates HAND2 gene regulatory networks in endocardial cells using single-cell transcriptomics to identify HAND2-dependent enhancers and their impact on cardiac morphogenesis.

The paper performs transcriptome-wide pseudouridylation analysis in Drosophila melanogaster, identifying thousands of Psi modifications across rRNAs, mRNAs, and non-coding RNAs, with implications for ribosome and mitochondrial function.

The paper introduces RoC-ITS, a method for high-resolution microbial community analysis using Nanopore sequencing, and demonstrates its accuracy in quantifying species abundance and identity.

The paper analyzes the potential for an autosomal X-shredder to become a Y-linked drive element in malaria mosquitoes and concludes it is unlikely due to suppression mechanisms.

This paper develops a TE-based authentication protocol for Drosophila cell lines to improve reproducibility by distinguishing between different cell lines and sub-lines.

The paper introduces RAIL, a method for constructing promoter-reporter libraries in Vibrio harveyi to identify promoter boundaries and regulatory sequences.