Author

Pasquale Piccolo

Federico II University HospitalORCID 0000-0002-8614-2581Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Alberto AuricchioiD· 1 shared Alessio ConciiD· 1 shared Anna CeresetoiD· 1 shared Annamaria CarissimoiD· 1 shared Christian MuelleriD· 1 shared Edoardo NuscoiD· 1 shared Fanny CollaudiD· 1 shared Federica EspositoiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

Alberto AuricchioORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintOct 28, 2026

Single-vector AAV delivery of En-ISPmu1 and donor DNA for in vivo targeted genome integration

Alessio Conci, Ilaria Bonuzzi, Matteo Ciciani…·Anna Cereseto

The paper describes the development of En-ISPmu1, a modified TnpB nuclease, and demonstrates its ability to achieve targeted genome integration in mouse liver with a single AAV vector.

DOI 10.64898/2026.10.26.761871

mouseCRISPR screen

𝕏 PostBluesky

GeneticsbioRxivPreprintMay 4, 2020

CHOP-c-JUN complex plays a critical role in liver proteotoxicity induced by mutant Z alpha-1 antitrypsin.

Sergio Attanasio, Gwladys Gernoux, Rosa Ferriero…·Nicola Brunetti‐Pierri

The paper identifies the CHOP-c-JUN complex as a key driver of liver proteotoxicity in AAT deficiency by enhancing SERPINA1 transcription and ATZ accumulation.

1 citation

mousehuman

𝕏 PostBluesky