PD-1 blockade enhances HIV-1 vaccine-induced CD8+ T-cell responses in PWH early ART-treated
Miguel Ángel Marín, Alba Ruiz, Dan Ouchi, Esther Jiménez‐Moyano, Ruth Peña, Oscar Blanch-Lombarte, Dan Gorman, Richard Barnard, Tomáš Hanke, Bonaventura Clotet, Bonnie J. Howell, Christian Brander, Beatriz Mothe, Júlia G. Prado
This study shows PD-1 blockade enhances HIV-1 vaccine-induced CD8+ T-cell responses in early ART-treated PWH, improving proliferation, IFN-gamma production, and activation.
EBioMedicine · Dec 9, 2025Peer-reviewedImmunology