Júlia G. Prado

This study shows PD-1 blockade enhances HIV-1 vaccine-induced CD8+ T-cell responses in early ART-treated PWH, improving proliferation, IFN-gamma production, and activation.

The paper identifies inducible HIV reservoirs in tonsillar, intestinal, and cervical tissues using tissue models, revealing tissue-specific markers and the effectiveness of different latency reversal agents.

This study evaluates the effect of combining antiretroviral therapy (ART) with TIGIT or KLRG1 blockade in humanized mice, showing improved HIV-1 suppression and delayed viral rebound.

Combining dendritic cell stimulation with anti-TIGIT antibodies enhances memory NK cell cytotoxicity against HIV-1 infected CD4+ T cells in vitro and in vivo.