Author

Yi Ting Chew

Yale UniversityORCID 0000-0002-8630-6910Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Microbiology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:phylogenetics / evolution· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Abigail J PorzucekiD· 1 shared Anderson Fernandes BritoiD· 1 shared Barney I. PotteriD· 1 shared Benjamin SobkowiakiD· 1 shared Caroline ColijniD· 1 shared Christine V. F. CarringtoniD· 1 shared Eng Eong OoIiD· 1 shared Isabel RancuiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperBioinformatics

Abigail J PorzucekORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Tracking two decades of global dengue virus lineage dynamics

Samantha Good, Abigail J Porzucek, Yi Ting Chew, Rafael Lopes, Naomi Rankin, Christine V. F. Carrington, Eng Eong OoI, Anderson Fernandes Brito, Verity Hill, Nathan D. Grubaugh

This study tracks DENV lineage dynamics over two decades using 37,828 genomes, revealing regional diversity patterns and the impact of COVID-19 on lineage persistence and spread.

bioRxiv · Oct 4, 2026 · PreprintBioinformatics

The global phylogeography of rapidly expanding multidrug resistant Ural lineage 4.2 Mycobacterium tuberculosis

Melanie H. Chitwood, Isabel Rancu, Yexuan Song, Barney I. Potter, Yi Ting Chew, Nelly Ciobanu, Valeriu Crudu, Caroline Colijn, Ted Cohen, Benjamin Sobkowiak

The paper identifies a rapidly expanding multidrug-resistant M. tuberculosis clade originating from Russia and circulating in Moldova, posing a threat to MDR-TB control.

Nature Communications · Mar 31, 2026Peer-reviewedMicrobiology

Precise and programmable C:G to G:C base editing in genomic DNA

Liwei Chen, Jung Eun Park, Peter Paa, Priscilla D. Rajakumar, Yi Ting Chew, Swathi N. Manivannan, Wei Leong Chew

This paper develops C:G to G:C base editors to correct specific SNPs in human cells, achieving up to 37% editing efficiency and 90% specificity.

bioRxiv · Jul 21, 2020 · PreprintSynthetic Biology