Author

Martin Yepes

Johns Hopkins UniversityORCID 0000-0002-8642-8440Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:E. coli· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Albert Y. LauiD· 1 shared Amilcar J. PereziD· 1 shared Brooke M. BrittoniD· 1 shared Jie XiaoiD· 1 shared Nicolás N. YehyaiD· 1 shared Ribo Xiong· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiophysics

Albert Y. LauORCID

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1 paper

Recent·Most cited

Substrate binding and activation mechanism of the essential bacterial septal cell wall synthase FtsW

Martin Yepes, Nicolás N. Yehya, Amilcar J. Perez, Ribo Xiong, Brooke M. Britton, Albert Y. Lau, Jie Xiao

This study defines the substrate binding and activation mechanism of FtsW using simulations, mutagenesis, and assays, revealing conserved residues and structural constraints involved in lipid II binding and catalysis.

bioRxiv · Feb 14, 2026 · PreprintBiophysics