Varun K. A. Sreenivasan

This study compares trio, singleton, and standard genome sequencing in rare disease diagnosis, finding trio sequencing has the highest diagnostic yield.

The paper shows adult mouse SCN astrocytes respond to glucocorticoids through GR activation, influencing circadian rhythms and highlighting astrocytic roles in time-keeping.

The paper uses single-cell RNA sequencing to systematically phenotype mouse genetic models, identifying molecular and cellular changes across multiple mutants and wildtypes.

The paper measures how membrane-cytoskeleton bonds in HNSCC cells rupture under tensile loading, finding a biphasic relationship with loading rate and catch-slip behavior.