Maternal smoking in early pregnancy disrupts placental function through syncytiotrophoblast and macrophage dysregulation.
Daniela Sofia Valdes, Jose Nimo, Olivia Nonn, Juliane Ulrich, Désirée Forstner, Sandra Haider, Miriam Ernhoefer-Reßler, Marc Pignitter, Dominik N. Müller, Ralf Dechend, Martin Gauster, Fabian Coscia, Florian Herse
This study shows maternal smoking disrupts placental function by altering syncytiotrophoblast and macrophage biology, leading to fetal growth restriction.
bioRxiv · Jul 10, 2025 · PreprintSystems Biology