Author

Laura H. McCulloch

NYU Langone HealthORCID 0000-0002-8676-5703Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Organism:yeast· 1

Frequent Co-Authors

Jef D. BoekeiD· 2 shared LESLIE ANN MITCHELLiD· 2 shared Ally Moyer· 1 shared Anthony D’Amato· 1 shared Anthony Staiti· 1 shared Antonio Spina· 1 shared Arden Snee· 1 shared Ardeshir Kianercy· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSynthetic Biology

Jef D. BoekeORCID

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2 papers

Recent·Most cited

Synthetic BiologyMolecular CellPeer-reviewedNov 8, 2023

Manipulating the 3D organization of the largest synthetic yeast chromosome

Weimin Zhang, Luciana Lazar‐Stefanita, Hitoyoshi Yamashita…·Jef D. Boeke

This paper synthesizes the largest eukaryotic yeast chromosome, synIV, and investigates how its 3D structure affects gene regulation and transcription.

37 citations

yeastDNA methylation

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GeneticsbioRxivPreprintJan 26, 2019

De novo assembly, delivery and expression of a 101 kb human gene in mouse cells

LESLIE ANN MITCHELL, Laura H. McCulloch, Sudarshan Pinglay…·Jef D. Boeke

The paper describes a pipeline for de novo assembly, delivery, and expression of a 101 kb human gene in mouse cells, demonstrating functional evaluation of a full-length gene.

7 citations

humanmouse

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