Integrative proteomics and transcriptomics of human T-cells reveals temporal metabolic reprogramming following TCR-induced activation
Harshi Thilanka Welegedara Weerakoon, Ahmed Mohamed, Yide Wong, Bhagya Senadheera, Oscar L. Haigh, Thomas S. Watkins, Stephen H. Kazakoff, Pamela Mukhopadhyay, Jason P. Mulvenna, John J. Miles, Michelle Mei Chih Hill, Ailin Lepletier
This study integrates proteomic and transcriptomic data from human T-cells to show time-dependent metabolic reprogramming and divergence in gene expression during activation.
bioRxiv · Mar 17, 2023 · PreprintSystems Biology