ImmunologybioRxivPreprint
Pulmonary delivery of antigen-enhanced BCG overcomes safety barriers in immunocompromised hosts and protects against TB in the absence of adaptive immunity.
Harindra Darshana Sathkumara, Guangzu Zhao, Andrew Calcino…·Andreas Kupz
This study shows that pulmonary delivery of ESAT-6-secreting BCG strains improves safety and protection against TB in immunocompromised mice, independent of adaptive immunity.
DOI 10.64898/2026.07.05.736631