Stephen H. Kazakoff

This study integrates proteomic and transcriptomic data from human T-cells to show time-dependent metabolic reprogramming and divergence in gene expression during activation.

The paper develops endometrial cancer PDX models that capture tumor heterogeneity and predict response to talazoparib.

The paper analyzes the innate immune response at injection sites after vaccination with a recombinant vaccinia vector, identifying immune signatures and gene expression patterns.

The paper maps chromatin interactions at 139 breast cancer risk signals using Capture Hi-C and identifies candidate target genes and functional mechanisms.

The paper identifies five distinct subtypes of colorectal cancer using DNA methylation profiling and links them to specific mutations and gene body methylation patterns.