Mahmoud E. S. Soliman

HIV-1 subtype C LTR Sp1IIIT5A mutant enhances transcription activity and Sp1 binding affinity

This study shows that the Sp1IIIT5A mutation in HIV-1C LTR increases transcription activity and Sp1 binding affinity, enhancing viral replication and potentially contributing to disease progression.

Differential gene expression profiling reveals potential biomarkers and pharmacological compounds against SARS-CoV-2: insights from machine learning and bioinformatics approaches

The paper identifies differentially expressed genes (DEGs) in COVID-19 patients and recovered individuals using machine learning, revealing potential biomarkers and therapeutic compounds.