Author

Young Hoon Koh

University of ChicagoORCID 0000-0002-8717-6089Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:deep learning· 1 Approach:mechanistic / dynamical model· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

Benoı̂t RouxiD· 1 shared Bernardo I. PintoiD· 1 shared Eduardo PerozoiD· 1 shared Francisco BezanillaiD· 1 shared Lydia BlachowicziD· 1 shared Ramon Mendoza UriarteiD· 1 shared Richa AgrawaliD· 1 shared Trayder ThomasiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiophysics

Benoı̂t RouxORCID

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1 paper

Recent·Most cited

Structure of the ILT Mutant Shaker K+ Channel and the Mechanism of Voltage Activation

Richa Agrawal, Ramon Mendoza Uriarte, Bernardo I. Pinto, Trayder Thomas, Lydia Blachowicz, Young Hoon Koh, Francisco Bezanilla, Eduardo Perozo, Benoı̂t Roux

The paper determines the cryo-EM structure of a Shaker K+ channel mutant and shows that voltage sensing domain activation induces a dynamic shift in the linker population equilibrium rather than directly pulling the gate open.

bioRxiv · Nov 13, 2025 · PreprintBiophysics