Author

Richa Agrawal

University of ChicagoORCID 0000-0001-9878-8999Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

Benoı̂t RouxiD· 2 shared Bernardo I. PintoiD· 2 shared Eduardo PerozoiD· 2 shared Francisco BezanillaiD· 2 shared Trayder ThomasiD· 2 shared Lydia BlachowicziD· 1 shared Ramon Mendoza UriarteiD· 1 shared Young Hoon KohiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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2 shared papersBiophysics

Benoı̂t RouxORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintSep 15, 2026

Mechanistical and structural basis of Kv channel inhibition by 4 aminopyridine

Bernardo I. Pinto, Richa Agrawal, Trayder Thomas…·Francisco Bezanilla

This study determines the structure of Kv channels bound to 4AP, showing it binds the closed state and enters via membrane-facing fenestrations, explaining its inhibitory mechanism.

DOI 10.64898/2026.09.12.751153

structural biologyexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivPreprintNov 13, 2025

Structure of the ILT Mutant Shaker K+ Channel and the Mechanism of Voltage Activation

Richa Agrawal, Ramon Mendoza Uriarte, Bernardo I. Pinto…·Benoı̂t Roux

The paper determines the cryo-EM structure of a Shaker K+ channel mutant and shows that voltage sensing domain activation induces a dynamic shift in the linker population equilibrium rather than directly pulling the gate open.

DOI 10.1101/2025.11.13.687653

cryo-EMdeep learning

𝕏 PostBluesky