BiophysicsbioRxivPreprint
Two functionally distinct amyloid-β intermediates link aggregation pathways to pathology in Alzheimer's disease
Agnieszka N. Urbanek, Alexander J. Dear, David Rhodes…·Suman De
This study identifies two distinct amyloid-β intermediates that drive Alzheimer's pathology and shows their suppression reduces plaque burden and improves cognition in mice.