Epigenetic Programming of Macrophage Phenotypes by STING-IRF3 Drives Inflammation in Ascending Thoracic Aortic Dissection
Bowen Li, Chen Zhang, Samantha Xu…·Ying H. Shen
This study identifies STING-IRF3-mediated epigenetic programming of macrophages as a driver of inflammation in aortic dissection, showing its role in pro-inflammatory bias and therapeutic potential.