Author

Dongjun Li

University of MichiganORCID 0000-0002-8739-5986Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Dongjun Li1 paper · Harvard University

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:multiome· 1

Frequent Co-Authors

Christopher GrunseichiD· 2 shared Vivian G. CheungiD· 2 shared Alan Bruzel· 1 shared Athena Marie ApfeliD· 1 shared Audrey M. WinkelsasiD· 1 shared Brian JohnsoniD· 1 shared George G. Harmison· 1 shared Jason A. WattsiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenetics

Christopher GrunseichORCID

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2 papers

Recent·Most cited

Allele-specific silencing of a dominant SETX mutation in familial amyotrophic lateral sclerosis type 4

Audrey M. Winkelsas, Athena Marie Apfel, Brian Johnson, George G. Harmison, Kimberly K. Diaz Perez, Dongjun Li, Vivian G. Cheung, Christopher Grunseich

The paper demonstrates that allele-specific siRNA can effectively silence a dominant SETX mutation in ALS4, restoring R-loop levels in patient cells.

Human Genetics and Genomics Advances · Apr 8, 2025Peer-reviewedGenetics

A transcriptional mechanism involving R-loop, m6A modification and RNA abasic sites regulates an enhancer RNA of APOE.

Jason A. Watts, Christopher Grunseich, Yesenia Rodriguez, Yaojuan Liu, Dongjun Li, Joshua T. Burdick, Alan Bruzel, Robert J. Crouch, Robert W. Mahley, Samuel H. Wilson, Vivian G. Cheung

The paper identifies an enhancer RNA, AANCR, regulated by R-loops, m6A modification, and RNA abasic sites that influences APOE expression and Alzheimer's disease susceptibility.

bioRxiv · May 1, 2022 · PreprintMolecular Biology