Cancer BiologyJournal of Biological ChemistryPeer-reviewed
Differential requirement of m6A reader proteins, IGF2BP2 and HNRNPA2B1 for the processing of N6-methyladenosine modified H19 lncRNA: Stability versus miR-675 biogenesis
Samarjit Jana, Abhishek Chowdhury, Kumaravel Somasundaram
This study shows that m6A reader proteins IGF2BP2 and HNRNPA2B1 differentially regulate H19 lncRNA processing, with IGF2BP2 enhancing stability and HNRNPA2B1 promoting miR-675 biogenesis, which drives glioma cell migration.
2 citations