LSD1 Performs Demethylase-Independent and Context-Specific Roles in Ewing Sarcoma
Rachel D. Dreher, Cenny Taslim, Ira J. Miller, John William Sherman, Ariunaa Bayanjargal, Emily R. Theisen
This study defines the enzymatic and nonenzymatic roles of LSD1 in Ewing sarcoma using genetic and pharmacological approaches, revealing gene repression and its impact on synapse function and e-cadherin targets.
Cancer Research Communications · Feb 24, 2026Peer-reviewedCancer Biology