Ariunaa Bayanjargal

This study defines the enzymatic and nonenzymatic roles of LSD1 in Ewing sarcoma using genetic and pharmacological approaches, revealing gene repression and its impact on synapse function and e-cadherin targets.

This study shows seclidemstat inhibits the transcriptional activity of multiple FET fusion oncoproteins in vitro, suggesting it as a promising treatment for FET-rearranged sarcomas.

This study investigates the role of the DBD-4 helix in EWSR1::FLI1's binding to GGAA microsatellites, showing its importance in genome regulation and oncogenic transformation in Ewing sarcoma.

The paper shows that alternative splicing of APOBEC3B generates mutagenic and non-mutagenic isoforms, with implications for bladder cancer progression and therapeutic targeting.