Author

John William Sherman

Nationwide Children's HospitalORCID 0000-0002-7998-9979Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

Emily R. TheiseniD· 2 shared Ariunaa BayanjargaliD· 1 shared Aundrietta D. DuncaniD· 1 shared Bingcong XiongiD· 1 shared Cenny TaslimiD· 1 shared E. John TokarskyiD· 1 shared Eranthie WeerapanaiD· 1 shared Galen C. RaskiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Emily R. TheisenORCID

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2 papers

Recent·Most cited

LSD1 Performs Demethylase-Independent and Context-Specific Roles in Ewing Sarcoma

Rachel D. Dreher, Cenny Taslim, Ira J. Miller, John William Sherman, Ariunaa Bayanjargal, Emily R. Theisen

This study defines the enzymatic and nonenzymatic roles of LSD1 in Ewing sarcoma using genetic and pharmacological approaches, revealing gene repression and its impact on synapse function and e-cadherin targets.

Cancer Research Communications · Feb 24, 2026Peer-reviewedCancer Biology

N'-(1-phenylethylidene)-benzohydrazide cytotoxicity is LSD1 independent and linked to Fe-S cluster disruption in Ewing sarcoma

John William Sherman, Galen C. Rask, Bingcong Xiong, E. John Tokarsky, Aundrietta D. Duncan, Eranthie Weerapana, Emily R. Theisen

This paper identifies that SP-2509 and SP-2577, LSD1 inhibitors, induce cell death in Ewing sarcoma through Fe-S cluster disruption, independent of LSD1 inhibition.

bioRxiv · Jun 20, 2025 · PreprintPharmacology & Toxicology