Author

Martin Beukema

University Medical Center GroningenORCID 0000-0002-8746-817XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Anke L. W. HuckriedeiD· 2 shared Jacqueline J. de Vries-IdemaiD· 2 shared Shuran GongiD· 2 shared Barbro N. MelgertiD· 1 shared Harshad P. PatiliD· 1 shared Nilima Dinesh KumariD· 1 shared Nils Doesburg· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 18 mutual co-author links

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2 shared papersImmunology

Anke L. W. HuckriedeORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 19, 2026

Polymorphonuclear neutrophils modulate the responses of human immune cells to vaccines in an in vitro blood cell culture system

Shuran Gong, Harshad P. Patil, Jacqueline J. de Vries-Idema…·Anke L. W. Huckriede

This study shows that polymorphonuclear neutrophils (PMNs) regulate vaccine-induced immune responses by modulating monocyte dynamics, T cell differentiation, and cytokine production in co-cultures with PBMCs.

DOI 10.64898/2026.06.15.732289

humanbulk RNA-seq

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MicrobiologybioRxivPreprintJun 4, 2026

Immune-competent apical out airway organoids reveal distinct antiviral strategies of macrophages, neutrophils, and monocytes during influenza infection

Martin Beukema, Jacqueline J. de Vries-Idema, Nilima Dinesh Kumar…·Barbro N. Melgert

The paper establishes an immune-competent airway organoid model to study how macrophages, neutrophils, and monocytes respond to influenza virus in the human upper airway.

1 citation

humanorganoid / primary culture

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