Author

Nicole K. Littlejohn

Scripps Research InstituteORCID 0000-0002-8755-967XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Supriya SrinivasaniD· 2 shared Alessandra FerrariiD· 1 shared Chung‐Chih LiuiD· 1 shared Emily A. Witham· 1 shared Emma Marie RobinsoniD· 1 shared Erik B. VanstrumiD· 1 shared Harkaranveer Ratanpal· 1 shared Jaleh S. MesgarzadehiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPhysiology

Supriya SrinivasanORCID

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2 papers

Recent·Most cited

PhysiologybioRxivNov 21, 2025

NK2R signaling governs intestinal lipid mobilization and mucosal inflammation

Pedro Antonio Perez, Chung‐Chih Liu, Alessandra Ferrari…·S R Srinivasan

This study identifies NK2R as a key regulator of intestinal lipid metabolism and mucosal inflammation, showing bidirectional effects on lipid mobilization and immune responses.

1 citation

mousebulk RNA-seq

NeurosciencePLoS GeneticsPeer-reviewedMar 26, 2018

Oxygen-sensing neurons reciprocally regulate peripheral lipid metabolism via neuropeptide signaling in Caenorhabditis elegans

Rosalind Hussey, Nicole K. Littlejohn, Emily A. Witham…·Supriya Srinivasan

This study shows that oxygen-sensing neurons in C. elegans regulate lipid metabolism through neuropeptide signaling, balancing fat loss based on oxygen and food availability.

35 citations

C. elegansexperimental assay