Author

Jakob Hofvander

Lund UniversityORCID 0000-0002-8787-1866Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Kevin B. JonesiD· 2 shared Lesley A. HilliD· 2 shared Martin HirstiD· 2 shared T. Michael UnderhilliD· 2 shared Torsten O. NielseniD· 2 shared Afroditi SotiriouiD· 1 shared Alvin Qiu· 1 shared Ana BanitoiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Kevin B. JonesORCID

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2 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedDec 2, 2025

Cell-of-origin epigenome underlies SS18::SSX-mediated transformation

Lesley A. Hill, R. Wilder Scott, Lauren A. Martin…·T. Michael Underhill

This study identifies the cell-of-origin of synovial sarcoma as a rare fibroblastic population and shows that SS18::SSX induces an embryonic-like mesenchymal stem cell phenotype.

8 citations

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMay 14, 2024

Synovial Sarcoma Chromatin Dynamics Reveal a Continuum in SS18:SSX Reprograming

Jakob Hofvander, Alvin Qiu, Kiera Lee…·Martin Hirst

This study examines the epigenomic states of synovial sarcoma using multi-omics analysis, revealing a continuum of epigenomic states and identifying H3K4me3 inhibition as a potential therapeutic strategy.

10 citations

humanChIP-seq

𝕏 PostBluesky