Author

Zimeng Zhai

Qingdao University of Science and TechnologyORCID 0000-0002-8790-5392Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Anji Wei· 1 shared Di YiniD· 1 shared Feng LiiD· 1 shared Huangying Le· 1 shared Jianjiang XuiD· 1 shared Jiaxu HongiD· 1 shared Lijia Tian· 1 shared Mengting Guo· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Anji Wei

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintApr 15, 2026

Application of Engineered NK-92 Cell Extracellular Vesicles in the Treatment of Systemic Lupus Erythematosus

Yu Sun, Zeyu Tang, Mengting Guo…·Xiaowei Dou

This study develops engineered NK-92 cell-derived extracellular vesicles targeting CD19 to treat SLE in mice, showing reduced B cells, improved renal function, and increased survival.

DOI 10.64898/2026.04.14.718139

mouseexperimental assay

Genetic & Genomic MedicinemedRxivPreprintFeb 21, 2023

In Vivo CRISPR Gene Editing in Patients with Herpes Stromal Keratitis

Anji Wei, Di Yin, Zimeng Zhai…·Jiaxu Hong

This study evaluates the safety and efficacy of in vivo CRISPR gene editing targeting HSV-1 in patients with herpes stromal keratitis, finding no detectable off-target effects or adverse events over 18 months.

3 citations

humanCRISPR screen