The paper identifies human single neuron representations of intertemporal decision-making in specific brain regions and their relation to reward preferences.

Scientific Reports · Jul 8, 2025Peer-reviewedNeuroscience

Human neural dynamics of real-world and imagined navigation

Martin Seeber, Matthias Stangl, Mauricio Vallejo Martelo, Uros Topalovic, Sonja Hiller, Casey H. Halpern, Jean‐Philippe Langevin, Vikram R. Rao, Itzhak Fried, Dawn S. Eliashiv, Nanthia Suthana

This study investigates hippocampal theta oscillations during real-world and imagined navigation, showing similar neural patterns and using a computational model to reconstruct imagined positions.

Nature Human Behaviour · Mar 10, 2025Peer-reviewedNeuroscience

A wearable platform for closed-loop stimulation and recording of single- neuron and local field potential activity in freely-moving humans

Uros Topalovic, Sam Barclay, Chenkai Ling, Ahmed Alzuhair, Wenhao Yu, Vahagn Hokhikyan, Hariprasad Chandrakumar, Dejan Rozgic, Wenlong Jiang, Sina Basir-Kazeruni, Sabrina L. Maoz, Cory S. Inman, Matthias Stangl, Jay L. Gill, Ausaf Bari, , Dejan M. Markovic

This paper introduces a wearable closed-loop neuromodulation system for recording single-neuron and local field potential activity in freely-moving humans.

Nature Neuroscience · Feb 20, 2023Peer-reviewedNeuroscience

Wireless Programmable Recording and Stimulation of Deep Brain Activity in Freely Moving Humans

Uros Topalovic, Zahra M. Aghajan, Diane Villaroman, Sonja Hiller, Leonardo Christov‐Moore, Tyler J. Wishard, Matthias Stangl, Nicholas R. Hasulak, Cory S. Inman, Tony A. Fields, Vikram R. Rao, Dawn E. Eliashiv, Itzhak Fried, Nanthia Suthana

This paper develops a wireless platform for intracranial EEG recording and deep brain stimulation integrated with wearable technologies in freely moving humans.

Neuron · Sep 17, 2020Peer-reviewedNeuroscience

Modulation of human intracranial theta oscillations during freely moving spatial navigation and memory

Zahra M. Aghajan, Diane Villaroman, Sonja Hiller, Tyler J. Wishard, Uros Topalovic, Leonardo Christov‐Moore, Nader Shaterian, Nicholas R. Hasulak, Barbara Jean Knowlton, Dawn E. Eliashiv, Vikram R. Rao, Itzhak Fried, Nanthia Suthana

This study examines theta oscillations in the human medial temporal lobe during spatial navigation and memory, finding their prevalence correlates with memory performance and movement direction.

bioRxiv · Aug 19, 2019 · PreprintNeuroscience

Theta Oscillations in the Human Medial Temporal Lobe during Real World Ambulatory Movement

Zahra M. Aghajan, Peter Schuette, Tony Fields, Michelle Tran, Sameed Siddiqui, Nick Hasulak, Thomas K Tcheng, Dawn Eliashiv, John Stern, Itzhak Fried, Nanthia Suthana

This study identifies high-frequency theta oscillations (6-12Hz) in the human medial temporal lobe during real-world ambulation, supporting conserved mechanisms for spatial navigation.

bioRxiv · Sep 28, 2016Neuroscience