BioengineeringActa BiomaterialiaPeer-reviewed
Localized Delivery of Growth Factors from Microparticles Modulate Osteogenic and Chondrogenic Gene Expression in Growth Factor-dependent Manner in an ex vivo Chick Embryonic Bone Model.
Hassan Rashidi, Helen C. Cox, Omar Qutachi…·Felicity R. A. J. Rose
The paper develops an ex vivo chick embryonic bone model using PLGA microparticles to study growth factor delivery effects on cell differentiation and tissue formation, showing that controlled release of BMP2 and FGF2 alters collagen deposition and cell morphology.
4 citations